How do I know if my TB is drug resistant?

Drug-Resistant TB

1. People do not complete a full course of TB treatment.
2. Health care providers prescribe the wrong treatment (the wrong dose or length of time)
3. Drugs for proper treatment are not available.
4. Drugs are of poor quality.

What is the difference between MDR and XDR TB?

Multidrug resistant tuberculosis (MDR-TB) is a strain of TB that cannot be treated with the two most powerful first-line treatment anti-TB drugs. Extensively drug resistant tuberculosis (XDR-TB) is a form of TB caused by bacteria that are resistant to several of the most effective anti-TB drugs.

What test can be used to test for drug resistant strains of TB?

Sputum tests The samples are tested for TB bacteria. Sputum samples can also be used to test for drug-resistant strains of TB .

Which test has highest sensitivity for TB?

If sputum smears and NAA tests are negative, and TB is still suspected, cultures are the most sensitive tests for TB. Culture is therefore very useful for diagnosing both smear-negative TB and drug-resistant TB.

Which of the following diagnostic test can be used to diagnose drug resistant tuberculosis?

The novel diagnostic test – called MTBDRsl – is a DNA-based test that identifies genetic mutations in MDR-TB strains, making them resistant to fluoroquinolones and injectable second-line TB drugs. This test yields results in just 24-48 hours, down from the 3 months or longer currently required.

What causes resistance in TB?

Drug resistance in TB remains a man-made phenomenon. It emerges as a result of spontaneous gene mutations in M. tuberculosis that render the bacteria resistant to the most commonly used anti-TB drugs. Among the reasons for this, the non-compliance with the treatment regimens is signaled as the first cause.

How do you detect drug resistance?

The standard method for identifying drug resistance is to take a sample from a wound, blood or urine and expose resident bacteria to various drugs. If the bacterial colony continues to divide and thrive despite the presence of a normally effective drug, it indicates the microbes are drug-resistant.

What is Genexpert test for TB?

Introduction: Gene-Xpert, a CBNAAT (catridge based nucleic acid amplification test) is a widely accepted diagnostic test for Tuberculosis. This test is a rapid diagnostic test for Tuberculosis detection as well as Rifampicin resistance in direct smear negative cases.

What is the confirmatory test for tuberculosis?

The Mantoux tuberculin skin test (TST) or the TB blood test can be used to test for M. tuberculosis infection. Additional tests are required to confirm TB disease. The Mantoux tuberculin skin test is performed by injecting a small amount of fluid called tuberculin into the skin in the lower part of the arm.

What is the difference between IGRA and Quantiferon?

QFT is an interferon-gamma (IFN-γ) release assay, commonly known as an IGRA, and is a modern alternative to the tuberculin skin test (TST, PPD or Mantoux). Unlike the TST, QFT is a controlled laboratory test that requires only one patient visit and is unaffected by previous Bacille Calmette-Guerin (BCG) vaccination.

How do you diagnose TB diagnosis?