How many people are diagnosed with Kleine-Levin syndrome?

It affects around 1/500 000 individuals. Patients are mostly male (68-78\% of cases) and adolescents (81\% of patients), with a mean age of onset of 15 years (range 4-82 years).

What symptoms might lead a doctor to suspect a patient has Kleine-Levin Syndrome?

Kleine-Levin syndrome is an extremely rare disorder characterized by the need for excessive amounts of sleep (hypersomnolence), excessive eating (compulsive hyperphagia), and behavioral abnormalities. Onset of symptoms associated with this disorder is extremely rapid. Such symptoms may persist for days to weeks.

How is KLS diagnosed?

To be diagnosed with KLS, a person must meet first the criteria for recurrent hypersomnia: Episodes of excessive sleepiness lasting between two days and five weeks. Episodes occur at least once every 18 months and often more frequently. Normal behavior and cognition between episodes.

Which of the following symptoms is associated with Kleine-Levin Syndrome also known as Sleeping Beauty disorder )?

Kleine–Levin syndrome (KLS), also called “Sleeping beauty syndrome” is a rare, disorder predominantly reported in adolescent males, characterized by recurrent episodes of hypersomnia and to various degrees, hyperphagia, cognitive disturbances, and hypersexuality.

How do you get tested for sleep disorders?

Polysomnography, also called a sleep study, is a comprehensive test used to diagnose sleep disorders. Polysomnography records your brain waves, the oxygen level in your blood, heart rate and breathing, as well as eye and leg movements during the study.

Can a blood test detect insomnia?

If the cause of insomnia is unknown, your doctor may do a physical exam to look for signs of medical problems that may be related to insomnia. Occasionally, a blood test may be done to check for thyroid problems or other conditions that may be associated with poor sleep. Sleep habits review.

What is Kleine-Levin syndrome in adults?

View Full Treatment Information. Definition. Kleine-Levin syndrome is a rare disorder that primarily affects adolescent males (approximately 70 percent of those with Kleine-Levin syndrome are male). It is characterized by recurring but reversible periods of excessive sleep (up to 20 hours per day).

What tests are used to diagnose keleine-Levin syndrome?

Kleine-Levin syndrome may be confirmed based upon excessive sleep requirements (hypersomnolence); the desire to eat all available food (compulsive hyperphagia); and hypersexuality. Certain medical tests may be performed to rule out other conditions such as epilepsy, brain lesions, meningitis or encephalitis.

How effective is lithium for treating Kleine-Levin syndrome?

Lithium, a drug used to treat serious mood disorders (affective) disorders, has been effective in some cases. One report detailed five adolescents with Kleine-Levin syndrome who received treatment with lithium. Episodes of excessive sleep were shortened by treatment with lithium and no behavioral symptoms were present.

Can Kleine-Levin syndrome be misdiagnosed as bipolar?

Diagnosing Kleine-Levin Syndrome. The symptoms of KLS – somnolence, hyperphagia and withdrawal – can mimic those of severe depression, sometimes followed by a brief period of high, manic energy that could lead to a misdiagnosis of bipolar disorder. Because of all these variables, all other possibilities need to be ruled out,…