What is difference between water content and moisture content?

Usually water content refers to wet basis while moisture content refers to a dry basis. So basically water content = (total weight – dry weight)/total weight and moisture content = (total weight – dry weight)/dry weight.

What is difference between KF and Lod?

The Important difference between KF and LOD is, KF determines only moisture content in the sample and LOD determines weight loss of sample due to sample drying including volatile impurities.

Is loss on drying same as moisture content?

“Moisture content” can however also refer to any other volatile substances (volatiles) including water in materials. In the context of techniques and methods for moisture content determination, the term “loss on drying” (LOD) is synonymous with “moisture content”.

What is water content in pharmaceuticals?

Water content, also known as moisture content, is a term associated with the amount of water held in a substance or material. In regards to the pharmaceutical industry, an in-depth understanding of the maximum moisture content allowable during the processes for each product is essential.

Why do we do Lod?

A method commonly used for moisture content determination is the loss-on-drying method, or LOD. It is used to specify many major quality specifications. This is based on the thermogravimetric principle, in which a substance is heated until no more weight is lost, that is, it is completely dry.

What is Karl Fischer reaction?

The principle of Karl Fischer titration is based on the oxidation reaction between iodine and sulphur dioxide. Water reacts with iodine and sulphur dioxide to form sulphur trioxide and hydrogen iodide. An endpoint is reached when all the water is consumed.

What is LOD method?

What is constant weight in Lod?

Dried To Constant Weight. “Dried to constant weight” means that drying shall be continued until two consecutive weighings, the second of which is taken after an additional drying period appropriate to the nature and quantity of the residue, do not differ by more than 0.50 mg per g of substance taken.

What is the content of water?

water, a substance composed of the chemical elements hydrogen and oxygen and existing in gaseous, liquid, and solid states. It is one of the most plentiful and essential of compounds.