What is flecainide challenge test?

Flecainide is a Sodium Channel Blocker drug. It is used to prevent abnormal heart rhythms (antiarrhythmic). Flecainide blocks the faulty sodium channels and unmasks ECG changes in those patients who have Brugada syndrome.

Can kids have Brugada syndrome?

Brugada syndrome is rarely diagnosed in children. Children who have it usually don’t have any symptoms, so parents are unaware of their condition. This syndrome may explain some cases of sudden infant death syndrome (SIDS).

What is Ajmaline challenge?

Ajmaline Challenges are a well-established clinical test. It is undertaken to see if you have a hidden form of Brugada Syndrome. The purpose of the test is to use a drug called Ajmaline to uncover the characteristic Electrocardiogram (ECG) changes of the syndrome.

Can Brugada syndrome be misdiagnosed?

Misdiagnosis of BrS can occur with ECG changes of early repolarisation, athlete’s heart, right bundle branch block, acute pericarditis, myocardial infarction, prinzmetal angina, arrhythmogenic right ventricular cardiomyopathy (ARVC), myocarditis, Duchenne muscular dystrophy, electrolyte disturbances and hypothermia [2] …

Can flecainide cause Brugada syndrome?

The ECG at the time of admission showed a Brugada pattern, triggered by a flecainide overdose (about 1 g), in association with an unknown dose of lamotrigine and quetiapine. After discontinuation of all medications, the Brugada pattern disappeared and his ECG showed no abnormalities.

What are the side effects of flecainide 50 mg?

Side effects of flecainide include:

• visual disturbances.
• dizziness.
• irregular heartbeat (arrhythmias)
• swelling.
• weakness.
• strong or irregular heartbeat (palpitations)
• fatigue.
• shakiness (tremors)

Can you live a long life with Brugada?

Brugada syndrome may be a major cause of sudden cardiac death in men under 40. People with Brugada syndrome on average die between the ages of 26 to 56 years, with an average age of 40 years. If treated appropriately, patients can have a normal lifespan.

Is Brugada syndrome curable?

There’s currently no cure for Brugada syndrome, but there are things you can do to reduce your risk of experiencing serious problems. If your doctor thinks your risk of developing a dangerously fast heartbeat is low, you might not need any treatment at first.

What is an adenosine challenge?

The adenosine challenge is a well-established clinical test, the purpose of which is to use a drug called adenosine to uncover the characteristic ECG (heart tracing) changes of an accessory pathway, to confirm the presence or absence of an accessory pathway.

Can you live a full life with Brugada syndrome?

It can do, although many people with Brugada syndrome can lead an entirely normal life.

Is Brugada syndrome fatal?

Complications of Brugada syndrome require emergency medical care. They include: Sudden cardiac arrest. If not treated immediately, this sudden loss of heart function, breathing and consciousness, which often occurs while sleeping, is fatal.