Can rituximab cause arrhythmia?

Infusion reactions associated with Rituximab therapy have been reported including cardiac arrhythmia such as monomorphic ventricular tachycardia, supraventricular tachycardia, trigeminy, and irregular pulse [2,3,4].

Does rituximab affect the heart?

Heart Problems: Rituxan may cause chest pain, irregular heartbeats, and heart attack. Your healthcare provider may monitor your heart during and after treatment with Rituxan if you have symptoms of heart problems or have a history of heart problems.

Who should not take rituximab?

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of rituximab injection to treat GPA and MPA in children 2 years of age and older. However, use of rituximab injection is not indicated in children younger than 2 years of age with GPA or MPA.

Can rituximab cause bradycardia?

However, for most of the time, the predominant rhythm was 2:1 AV block with continued occurrence of episodes of high-grade AV block and junctional escape rhythm.

Can Rituxan cause heart palpitations?

This medicine may cause heart and heart rhythm problems (eg, heart attack, arrhythmia, cardiogenic shock). Check with your doctor if you have chest pain or discomfort, pain or discomfort in the arms, jaw, back, or neck, dizziness, fainting, fast, slow, or irregular heartbeat, cool, sweaty skin, or trouble breathing.

Can rituximab cause tachycardia?

Initial rituximab infusion reportedly causes adverse reactions in 87\% of patients. Most patients experience fever, chills, and rigors. In a minority of patients, arrhythmias (monomorphic VT, supraventricular tachycardia, trigeminy, and irregular pulse) have been reported during therapeutic infusion.

Does Rituxan raise blood pressure?

A mild to moderate change in blood pressure may also occur during infusion. In a previous study of rheumatoid arthritis subjects, a quarter of the subjects had a decrease in blood pressure, whereas a mild to moderate increase in blood pressure was also common. Your doctor will monitor you for these events.

How safe is rituximab?

Over 540,000 patients worldwide have now received rituximab and serious adverse reactions have occurred in a small minority of patients, but for the great majority of patients, rituximab is safe and well tolerated.

What steroid is given with rituximab?

Rituxan for granulomatosis with polyangiitis (GPA) The GPA must be moderate to severe. For this purpose, Rituxan is used with drugs called glucocorticoids, such as prednisone.

Does rituximab cause tachycardia?

Can rituximab cause cardiomyopathy?

Rituximab has been reported to cause hypotension, hypoxia, acute myocardial infarction, arrhythmias, and cardiogenic shock during the infusion process. There are also reported incidences where rituximab has caused non-ischaemic dilated cardiomyopathy.