What is antigenicity in zoology?

Definition. (1) The capacity of a molecule or an antigen to induce an immune response, that is to be recognized by and interact with an immunologically specific antibody or T-cell receptor. (2) The measure of the ability of a substance to produce immunity.

What does antigenic mean?

(AN-tih-jen) Any substance that causes the body to make an immune response against that substance. Antigens include toxins, chemicals, bacteria, viruses, or other substances that come from outside the body. Body tissues and cells, including cancer cells, also have antigens on them that can cause an immune response.

What is an example of antigenic variation?

Examples of random antigenic variation are those that occur in viruses such as the influenza virus and the human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS). The major antigenic components of these viruses are glycoproteins that make up their viral coat.

What are the determinants of antigenicity?

Property of antigens/ Factors Influencing Immunogenicity

• Foreignness. An antigen must be a foreign substances to the animal to elicit an immune response.
• Molecular Size.
• Chemical Nature and Composition.
• Physical Form.
• Antigen Specificity.
• Species Specificity.
• Organ Specificity.
• Auto-specificity.

What is the difference between antigenicity and immunogenicity?

The term immunogenicity refers to the ability of a substance to induce cellular and humoral immune response, while antigenicity is the ability to be specifically recognized by the antibodies generated as a result of the immune response to the given substance.

How would you define antigenicity and antigenic properties?

Antigen is a substances usually protein in nature and sometimes polysaccharide, that generates a specific immune response and induces the formation of a specific antibody or specially sensitized T cells or both. It is also called antigenic determinants. Autoantigens, for example, are a person’s own self antigens.

What is immunogenicity and antigenicity?

What are the antigenic properties?

The term “antigenic properties” is used to describe the antibody or immune response triggered by the antigens on a particular virus. “Antigenic characterization” refers to the analysis of a virus’ antigenic properties to help assess how related it is to another virus.

What do you mean by antigenic specificity?

Antigenic specificity is the ability of the host cells to recognize an antigen specifically as a unique molecular entity and distinguish it from another with exquisite precision.

Why is antigenicity important?

Antigenic variation not only enables the pathogen to avoid the immune response in its current host, but also allows re-infection of previously infected hosts. Immunity to re-infection is based on recognition of the antigens carried by the pathogen, which are “remembered” by the acquired immune response.

What are the factors of antigenicity?