Can you develop tolerance to Vyvanse?

For example, misuse of central nervous system stimulants such as Vyvanse can hasten the development of tolerance, physiological dependence, and addiction. Some degree of tolerance and dependence may develop even in people who take the drug as prescribed.

Does Vyvanse change your brain chemistry?

Vyvanse works by altering the balance of chemicals in your brain and increasing norepinephrine and dopamine levels. Norepinephrine is a stimulant, and dopamine is a naturally occurring substance that stimulates feelings of pleasure and reward. If you have ADHD, you may notice an improvement in your attention span.

Does tolerance to stimulants develop rapidly?

Unfortunately, a tolerance to stimulants develops rapidly, and this can spiral quickly into addiction. Learn more about the historical use of stimulants, what issues they’re used to treat, and what the quick tolerance development can lead to.

Does Vyvanse cause long term damage?

Rarely, Vyvanse can cause side effects that last longer or that cause long-term problems. These effects can include: cardiovascular (heart and blood vessel) problems, including increased blood pressure, heart attack, and stroke* blood circulation problems in your fingers and toes, including Raynaud’s disease*

Does Vyvanse cause dopamine depletion?

Vyvanse affects the dopamine and norepinephrine systems in the brain in the same way as Adderall, which is another ADHD medication. A few hours after a person stops taking Vyvanse, it starts to leave their system, which leads to a chemical imbalance in the brain.

Can you build a tolerance to dopamine?

There is no such thing as “dopamine tolerance”. The term is a kind of pseudoscientific metaphor associated with the equally pseudoscientific term “dopamine fasting”. Dopamine is not the pleasure molecule.

Can you build up tolerance to Adderall?

Complex dopamine theory and clinical studies suggest that stimulant medications may have the potential to cause tolerance and dependence over time but the data are unclear.

Does Adderall lose potency?

Adderall does expire, as most all medicines do, but what does this mean? Most drugs tend to be fully potent for years after their expiration date, and Adderall is likely no exception. It may gradually lose some potency over the years, but most of the original active ingredient probably remains.