How is Thallium-201 used?

Thallium-201 is a radiopharmaceutical agent used in the diagnosis of coronary artery disease and parathyroid hyperactivity. Other useful applications for a thallium-201 scan, like tumor diagnosis and olfacto-scintigraphy, are being explored and have shown promising results in various studies.

What is Thallium-201 used for in nuclear medicine?

Thallium-201 is a radiopharmaceutical used in myocardial perfusion imaging (MPI) using either planar or single photon emission computed tomography (SPECT) techniques for the diagnosis and localization of myocardial infarction.

What radiation does Thallium-201?

Tl-201 emits emitting mainly X-rays of energy 67–82 keV (88\% abundance) and gamma photons of 135 and 167 keV (12\% abundance). X or gamma rays could not be visible.

What is thallium imaging?

A thallium (or cardiolite) scan uses a radioactive tracer to see how much blood is reaching different parts of your heart. These tests are the more common forms of tests called nuclear medicine scans. You may also hear them called: thallium myocardial imaging.

What is thallium 201 contrast material?

Thallium-201 (Th-201) is a radiopharmaceutical used for scintigraphy, primarily of the myocardium. The element thallium is treated by the body as an analog of potassium; it is produced in a cyclotron by bombarding thallium-203 with protons.

How is thallium 201 injected?

Thallous Chloride Tl-201 Injection (thallous chloride) is supplied in an isotonic solution as a sterile, non-pyrogenic diagnostic radiopharmaceutical for intravenous administration.

How is Thallium 201 injected?

What is thallium used for?

Uses of thallium Thallium is used in photoresistors, infrared optical equipment, low melting glasses and several other applications. Thallium sulfate has been used as a rodent and ant killer because it’s odorless and tasteless. However, the use of the product has been prohibited since 1972 in the United States.

How does a thallium scan work?

Thallium scan: A method of examining the heart to obtain information about the blood supply to the heart muscle. In the scan, special cameras take a series of pictures of the heart. Radioactive sestamibi is injected into the bloodstream and serves as a tracer.

How is Thallium 201 made?

The herein-proposed process for producing thallium-201 resides in that a target from pure lead-206 enriched for at least 95\%, is subjected to irradiation with a bunch of protons having an energy of 50 to 70 MeV, this resulting in a reaction /sup 206/Pb(p,6n)/sup 201/Bi, the irradiated target is kept for a period of …

Is thallium 201 toxic?

The radioisotope thallium-201 (as the soluble chloride TlCl) is used in small amounts as an agent in a nuclear medicine scan, during one type of nuclear cardiac stress test. Soluble thallium salts (many of which are nearly tasteless) are highly toxic, and they were historically used in rat poisons and insecticides.

Where is thallium 201 found?

Sources of thallium Thallium is found as a mineral in the elements crooksite, lorandite and hutchinsonite. It’s also found as a trace element in iron pyrite and obtained from this ore by roasting the mineral. Small amounts of thallium are found in manganese nodules on the ocean floor.