Are thyroid problems common with Down syndrome?

Hypothyroidism is also common in adults with Down syndrome and can lead to symptoms of fatigue, mental sluggishness, weight fluctuations and irritability. Studies of adults with Down syndrome vary widely, but the incidence of thyroid disease in adults with Down syndrome is believed to be between 13\% and 50\%.

What should a child’s TSH be?

In the neonatal period, mild hypothyroidism can be defined by the presence of a TSH value between 6 and 20 mIU/L and normal FT4 levels. After the neonatal period, SH can be defined mild if TSH ranges between 4.5 and 10 mIU/L. The management of mild hypothyroidism in childhood is challenging.

Is TSH 3.5 Too high?

The normal range of TSH levels in adults is between 0.4 to 4.0 mIU/L (milli-international units per liter). Some research suggests that this range should actually be more like 0.45 to 2.5 mIU/L. The TSH range may also vary slightly based on the testing facility where your blood is being analyzed.

Is hypothyroidism associated with Down syndrome?

People who have Down’s syndrome usually tend to develop hypothyroidism but sometimes they can have hyperthyroidism although this is much less common. Many symptoms may indicate a person has a thyroid issue and the balance of symptoms may be different from person to person.

Can maternal hypothyroidism cause Down syndrome?

The observation that thyroid disease is frequent in mothers of children with Down syndrome (DS) has suggested that maternal thyroid antibodies could be a factor predisposing to trisomy 21 in their offspring.

What is high TSH kids?

A high TSH level typically shows that the thyroid is underactive (called primary hypothyroidism). If the TSH is high but the FT4 or FTI is normal, the condition is called subclinical hypothyroidism (which means very mild hypothyroidism).

What does a TSH level of 5.6 mean?

In the absence of symptoms, and if other thyroid tests are normal, TSH levels between 5.6 and 10 are considered subclinical, a level that indicates possible early-stage disease. A TSH level above 10 indicates a thyroid disorder.