Guidelines

Does high cholesterol always mean atherosclerosis?

Does high cholesterol always mean atherosclerosis?

If your cholesterol is too high, it builds up on the walls of your arteries. Over time, this buildup is known as atherosclerosis. This condition causes arteries to become narrowed, and the narrowed blood vessels reduce blood flow to the heart.

Can you have high cholesterol no plaque build up?

It is an early sign of heart disease, even in patients with no symptoms. Researchers also found that patients with higher low-density lipoprotein cholesterol, often referred to as LDL or “bad” cholesterol, were more likely to have plaque build-up than those with lower cholesterol levels.

Can you have atherosclerosis with normal cholesterol?

LDL-C, even at levels currently considered normal, is independently associated with the presence and extent of early systemic atherosclerosis in the absence of major conventional cardiovascular risk factors.

Does everyone with high cholesterol get heart disease?

Dietary cholesterol is not linked to the risk of heart disease. High-cholesterol foods like eggs have been shown to be safe and healthy.

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Does everyone have atherosclerosis?

Everyone who has had an atherosclerotic event, be it from involvement of the coronary arteries, carotid arteries, aorta, or peripheral arteries. The goal in patients with symptomatic atherosclerosis is LDL cholesterol <100 mg/dL. The goal in persons without symptomatic atherosclerosis should be the same.

What is the symptoms of atherosclerosis?

As arteriosclerosis progresses, clogged arteries can trigger a heart attack or stroke, with the following symptoms:

  • Chest pain or pressure (angina)
  • Sudden arm or leg weakness or numbness.
  • Slurred speech or difficulty speaking.
  • Brief loss of vision in one eye.
  • Drooping facial muscles.
  • Pain when walking.
  • High blood pressure.

Who is at highest risk of developing atherosclerosis?

By the time you’re middle-aged or older, enough plaque has built up to cause signs or symptoms. In men, the risk increases after age 45. In women, the risk increases after age 55. Family history of early heart disease.

How does LDL cause atherosclerosis?

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In the early stages of atherosclerosis, LDL that has entered the artery wall attracts and is engulfed by important immune system cells called macrophages that ingest, or “eat,” LDL particles. LDL-laden macrophages become foam cells that promote inflammation and further the development of atherosclerotic plaques.

Where is atherosclerosis most common?

The most common locations for atherosclerosis are:

  • Arteries in the heart, known as coronary atherosclerosis;
  • Arteries that supply the legs, known as peripheral arterial disease (pad);
  • Arteries that supply the brain, known as carotid artery disease.