What is the treatment of Hirayama disease?

As “Hirayama disease” is considered a self-limited disease and often stops progressing after 1–5 years of onset, the mainstay of treatment consists of preventing neck flexion using a cervical collar to halt further progression.

How can stem cells be used in the treatment of diseases?

In stem cell transplants, stem cells replace cells damaged by chemotherapy or disease or serve as a way for the donor’s immune system to fight some types of cancer and blood-related diseases, such as leukemia, lymphoma, neuroblastoma and multiple myeloma. These transplants use adult stem cells or umbilical cord blood.

Is Hirayama disease hereditary?

Unlike other forms of lower motor neuron diseases, Hirayama’s disease is not one that is believed to be hereditary. For people who have this disease, ‘fasciculations,’ or involuntary muscle twitches, are rare.

What causes Hirayama disease?

The condition is caused by a tight dural sac in the cervical canal that leads to chronic ischemic changes to the anterior horn cells. Although commonly considered a non-progressive and self-limiting disease, this has been noted to be a source of significant disability for some affected individuals.

How do stem cells treat Alzheimer’s disease?

Stem cell therapy is a unique approach to treating Alzheimer’s Disease. It involves the systemic introduction of Mesenchymal Stem Cells into the body via IV. When introduced in large quantities, these stem cells can find inflammation within the body and repair it.

What are the side effects of stem cells?

Stem cells. The most common side effects after transplant are fatigue, lack of appetite, diarrhea, nausea, and vomiting. Many patients also continue to deal with hair loss, skin rash, swelling, weight loss or gain, fatigue, change in taste/appetite, or decrease in sexual desire.

What is the cause of Hirayama disease?

How is Hirayama disease diagnosed?

The key to diagnose this disease is based on the typical clinical features and dynamic MRI study when the neck is flexed. MR studies in flexion show not only the anterior displacement of the posterior wall but also a well-enhanced crescent-shaped lesion in the posterior epidural space of the lower cervical canal.

Is Hirayama disease genetic?

There is a debate as to whether Hirayama disease is an unusual neck flexion induced cervical myelopathy or an intrinsic motor neuron disease. Despite being a sporadic disorder, familial forms have been occasionally described, with either autosomal recessive or dominant inheritance.