What is trametinib used for?

What is trametinib? Trametinib is used alone or in combination with another medicine called dabrafenib (Tafinlar) to treat certain types of cancer in people who have a “BRAF” gene mutation.

What is Mekinist used for?

TAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic NSCLC), and that has a certain type of abnormal “BRAF V600E” gene.

What is trametinib target?

Trametinib is a targeted therapy that targets the MEK 1 and MEK 2 protein (kinase) within the cancer cell. It is usually given in combination with a BRAF kinase inhibitor. The BRAF gene plays an important role in both normal and cancer cells.

When should I take trametinib?

Trametinib comes as a tablet to take by mouth. It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after a meal. Take trametinib at around the same time every day.

What are the side effects of Mekinist?

Common side effects of TAFINLAR and MEKINIST in people with NSCLC include:

• Fever.
• Fatigue.
• Nausea.
• Vomiting.
• Diarrhea.
• Dry skin.
• Decreased appetite.
• Rash.

What kind of drug is Mekinist?

Mekinist (trametinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Mekinist is used alone or in combination with another medicine called dabrafenib (Tafinlar) to treat certain types of cancer in people who have a “BRAF” gene mutation.

Is Mekinist chemotherapy?

Mekinist is the trade name for the generic chemotherapy drug trametinib. In some cases, health care professionals may use the generic name trametinib when referring to the trade name Mekinist. Drug type: Mekinist is a targeted therapy.

Is Mekinist a targeted therapy?

TAFINLAR + MEKINIST is a targeted therapy that can be used for 2 different types of melanoma treatment: Adjuvant (after surgical removal) treatment of BRAF+ melanoma, to help prevent your melanoma from coming back after surgery.

How long can you take Tafinlar and Mekinist?

How long do I take TAFINLAR + MEKINIST? Keep taking TAFINLAR® (dabrafenib) capsules + MEKINIST® (trametinib) tablets for as long as your health care provider tells you. If you are experiencing side effects, please tell your health care provider as soon as possible.

Is Mekinist a chemo drug?

Mekinist is the trade name for the generic chemotherapy drug trametinib. In some cases, health care professionals may use the generic name trametinib when referring to the trade name Mekinist.

How long can you take Mekinist?

Recommended Dosage For The Adjuvant Treatment Of Melanoma The recommended dosage of MEKINIST is 2 mg orally taken once daily in combination with dabrafenib until disease recurrence or unacceptable toxicity for up to 1 year. Refer to the dabrafenib prescribing information for recommended dabrafenib dosing information.

Does Mekinist cause high blood pressure?

Mekinist can cause new or worsening high blood pressure (hypertension). Your healthcare provider should check your blood pressure during treatment with Mekinist.