What is the duration of MDR TB?

MDR- and XDR-TB need prolonged treatment duration, from 18 to 24 months after sputum culture conversion, as recommended by the World Health Organization (WHO) [2]. A prolonged duration of treatment may lead to poor adherence, higher cost and undue toxicity.

What methods monitor the effectiveness of TB treatment?

Monitoring response to treatment is done through regular history taking, physical examination, chest radiograph and laboratory monitoring. The classic symptoms of TB – cough, sputum production, fever and weight loss – generally improve within the first few weeks.

How many weeks is a TB treatment?

Regimens for treating TB disease have an intensive phase of 2 months, followed by a continuation phase of either 4 or 7 months. The continuation phase should be extended to 28 weeks for patients who have cavitation on the intensive chest film and positive sputum cultures after 2 months of treatment.

How is MDR TB diagnosed?

It has been reported in 117 countries worldwide. Drug resistance can be detected using special laboratory tests which test the bacteria for sensitivity to the drugs or detect resistance patterns. These tests can be molecular in type (such as Xpert MTB/RIF) or else culture-based.

What is TB MDR?

Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB medications (drugs), isoniazid and rifampin.

When is a patient diagnosed as having multi drug resistant MDR TB?

FASTPlaque-Response is a phage amplification-based test, and has been developed for direct use on sputum specimens. Drug resistance is diagnosed when M tuberculosis is detected in samples that contain the drug (ie, RIF).

What is MDR TB?

Multidrug-resistant TB (MDR TB) is caused by an organism that is resistant to at least isoniazid and rifampin, the two most potent TB drugs. These drugs are used to treat all persons with TB disease.

What is MDR-TB?