Which statin is least likely to cause diabetes?

In a network meta-analysis, pravastatin had the lowest risk of inducing new-onset DM among the high-dose statin therapy (atorvastatin 80 mg, rosuvastatin 20 mg, simvastatin 40 mg, and pravastatin 40 mg), but the difference was not statistically significant [58].

Which statin does not cause insulin resistance?

On the contrary, in small studies of 18 to 20 individuals that quantified insulin resistance by direct methods, insulin resistance did not significantly increase after treatment with pravastatin, simvastatin, or rosuvastatin.

Which statin has the least amount of side effects?

In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.

What is the safest statin to take?

Simvastatin and pravastatin had the best safety profile, according to this review. Overall, the researchers found a 9 percent increased risk of type 2 diabetes in people taking statins.

Which is the best statin for diabetics?

As mentioned, the ADA recommends moderate- and high-intensity statins for people with diabetes. In general, the ADA suggests using a lower potency statin for a person with diabetes only when they can’t tolerate a higher dose. Pravastatin (Pravachol) and lovastatin (Altoprev) are two lower-potency options.

Which statin has highest risk of diabetes?

High-intensity statins, such as atorvastatin 80 mg and rosuvastatin 20 mg, are associated with a higher excess risk of diabetes than moderate-intensity statins, such as atorvastatin 10 mg, simvastatin 20-40 mg, or pravastatin 40 mg.

Does atorvastatin cause insulin resistance?

Atorvastatin causes insulin resistance and increases ambient glycemia in hypercholesterolemic patients.

Which statin is best for diabetics?

Are statins recommended for diabetics?

High-dose statin therapy is recommended for all patients with diabetes with a history of clinical atherosclerotic CVD or with at least one additional CVD risk factor. Moderate-dose statin therapy is also suggested for patients younger than 40 or older than 70 who have CVD risk factors.

Is Rosuvastatin safe for diabetics?

Rosuvastatin is one of the most potent statins available. Several studies have shown that it effectively reduces LDL cholesterol to recommended targets in diabetics. Moreover, rosuvastatin modestly increases HDL cholesterol and decreases triglycerides.