Why does GERD cause anemia?

“The loss of iron clearly equates to loss of blood. The most prominent place for loss of blood is in the GI tract.” A hernia—one potential cause of the anemia—can mimic, as well as exacerbate, the symptoms of GERD, says Dr.

Can GERD cause iron deficiency anemia?

Researchers in Australia have conducted the first population-based study of its kind and found that proton pump inhibitors (PPIs), a class of acid suppressants that many people take for heartburn, gastroesophageal reflux disease (GERD), and peptic ulcers, are associated with iron deficiency.

Does GERD affect hemoglobin?

We studied the relationship between anemia and chronic diseases of the upper gastrointestinal tract in patients with CHD. Patients with CHD and gastroesophageal reflux disease (GERD) had the lowest hemoglobin levels and erythrocyte counts in the absence of pronounced independent effect of GERD.

Can gastrointestinal problems cause anemia?

Iron deficiency anemia (IDA) is associated with a number of pathological gastrointestinal conditions other than inflammatory bowel disease, and also with liver disorders. Different factors such as chronic bleeding, malabsorption and inflammation may contribute to IDA.

Does esophagitis cause anemia?

Objective: Iron-deficiency anemia is sometimes attributed to esophagitis and hiatal hernia; however, because these GI conditions are so common, such an association could be coincidental.

Can omeprazole cause iron deficiency anemia?

There are few case reports of iron deficiency induced by long-term omeprazole use and the effect of omeprazole on iron replacement therapy. In contrast, Koop and Bachem6 concluded that iron and ferritin malabsorption was unlikely to occur during the first 3 to 4 years of omeprazole therapy.

Does iron cause acid reflux?

Iron supplements. This mineral can help your body to make more red blood cells and fight iron-deficiency anemia, but it can also cause acid reflux, upset stomach, and constipation. Try taking iron pills with food and avoid taking them at bedtime.

Does gastroenterologist treat anemia?

Patients with iron deficiency anemia of unknown etiology are frequently referred to a gastroenterologist because in the majority of cases the condition has a gastrointestinal origin. Proper management improves quality of life, alleviates the symptoms of iron deficiency, and reduces the need for blood transfusions.

Does iron infusion cause GERD?

However, oral iron treatment can cause gastrointenstinal side effects, such as acid reflux, constipation, diarrhea, nausea or flatulence, and sometimes, treatment is not effective [6].

Can omeprazole cause high iron levels?

Some studies suggest that prolonged omeprazole use for at least 3 to 4 years is unlikely to cause iron and ferritin malabsorption,6 whereas Sarzynski et al9 found that among adults on long-term PPI therapy, defined as >1 year, there was a significant decrease in hematologic indices from baseline.

What drugs interfere with iron absorption?

Iron decreases the absorption of the following medications:

• Tetracyclines: Antibiotics that include doxycycline (Vibramycin), minocycline (Minocin), and tetracycline.
• Quinolones: Antibiotics that include ciprofloxacin (Cipro), norfloxacin (Noroxin), and levofloxacin (Levaquin).