Is oxyclozanide safe in pregnancy in animals?

At normal oxyclozanide dose levels, cattle may show slight softening of the faeces with the occasional animal showing increased frequency of defecation and transient inappetance. The product can be safely administered to pregnant or lactating animals.

Is levamisole safe for pregnant cattle?

Levamisole has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of embryotoxicity.

What is the use of oxyclozanide?

Oxyclozanide is a salicylanilide anthelmintic, used for the treatment and control of fascioliasis in cattle, sheep and goats. It is formulated as an oral drench containing oxyclozanide only or in combination with levamisole hydrochloride or oxfendazole or as a powder to be incorporated in the feed.

Is Oxfendazole safe in pregnant cattle?

Oxfendazole proved to be safe and without teratogenic effect when administered repeatedly and in overdose to heifers during early pregnancy and had no adverse effect on fertility in rams during repeated dosing over periods of eight to 10 weeks.

What is levamisole hydrochloride?

Levamisole is an antihelminthic drug that was commonly used for the treatment of parasitic, viral, and bacterial infections. 4. It was manufactured by Janssen and first used in 1969 as an agent to treat worm infestations 6 Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer.

Is levamisole safe for pregnant goats?

Albendazole is effective against adult liver flukes, but should not be used in pregnant or lactating females. Levamisole (Tramisol®), also called a “clear dewormer” is broad spectrum and effective against arrested larvae. However, it has a narrower margin of safety, especially in the injectable form.

Is levamisole safe for pregnant goat?

Is levamisole safe for pregnant animals?

Levamisole should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby. No studies have been done in animals, and no well-controlled studies have been done in pregnant women.

What does Levafas Diamond cover?

Levafas Diamond Fluke and Worm Drench should be used in cases of parasitic gastroenteritis and lungworm caused by those organisms sensitive to treatment with Levamisole hydrochloride.

What is Nilzan?

NILZAN® Suspension is a broad spectrum drench for the control of susceptible roundworms including lungworm in sheep. RECOMMENDED FOR Doctors, hospitals and Registered Medical Practitioners. NILZAN® Suspension is a broad spectrum anthelmintic for fluke & roundworms infestations.

What is Oxfendazole used for?

Oxfendazole is a broad spectrum benzimidazole anthelmintic. Its main use is for protecting livestock against roundworm, strongyles and pinworms. Oxfendazole is the sulfoxide metabolite of fenbendazole. Oxfendazole is an anthelmintic (wormer) compound used in veterinary practice.

What is fenbendazole used for?

Fenbendazole is widely used as an antiparasitic agent against various gastrointestinal parasites, such as pinworms, giardia, roundworms, hookworms, Taenia solium, and pulmonary paragonimiasis [6-13]. The agent is used in several animal species, that is, dogs, cats, rabbits, rats, horses, sheep, and cattle [6-15].

Can you give oxyclozanide to a pregnant dog?

Yes it is safe to give oxyclozanide to a pregnant livestock animal (cattle, buffalo, sheep, goat). However like any other drug, it should be cautiously used in advanced pregnant animals which are in the last month of pregnancy. Dogs often hide signs of illness — Look for these clues instead.

Is oxyclozanide toxic for oral administration?

The acute and 28-day repeated oral toxicity of oxyclozanide were carried out to supply the toxicity of oxyclozanide and to provide guidance for phase II clinical trials. In this study, we evaluated the acute and subacute toxicity of oxyclozanide in rats for oral administration.

How much oxyclozanide can you give a cow?

Two doses of oxyclozanide 18.7 mg/kg 2 days apart, or a single oral dose of hexachlorophene 20 mg/kg, give consistent results against immature paramphistomes in cattle, but hexachlorophene may show toxicity at this dose rate and is therefore not preferred as a treatment.

Is oxyclozanide an effective anthelmintic?

Oxyclozanide is an effective anthelmintic and has shown good properties in other ways including anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity. This study aimed to investigate the acute and subacute 28-days repeated dose oral toxicity of an oxyclozanide suspension in Wistar rats.