What is F note value?

F0 value is the time in minute for the specified temperature that gives the same thermal lethality as at 121 °C in one minute. Related: Determination of Z-Value. It explains that temperature is not an important factor in thermal sterilization but lethality is important.

What is Z value in microbiology?

Z-value is a term used in microbial thermal death time calculations. It is the number of degrees the temperature has to be increased to achieve a tenfold (i.e. 1 log10) reduction in the D-value.

How do you find the F value of a autoclave?

F0 Value, D Value and Z Value Calculations

1. For example, if D-Value at 121ºC is 1.5 min & Z-Value is 10ºC.
2. Sterility Assurance Level (SAL)
3. Required SAL for steam sterilization process = 10 -6 or better.
4. Fo = D121 ( logNo – log N )
5. Where No= Initial spore population (B.

What is an F0 value?

F0 Value (Equivalent Exposure Time) F0 value is the equivalent exposure time at 121.1°C to that of the actual exposure time at a variable temperature calculated with a temperature coefficient of the destruction of 10°C.

What is DZ and F value?

The z-value of an organism is the temperature, in degrees Fahrenheit, that is required for the thermal destruction curve to move one log cycle. While the D-value gives us the time needed at a certain temperature to kill an organism, the z-value relates the resistance of an organism to differing temperatures.

What is 12D concept?

12D concept refers to thermal processing requirements designed to reduce the probability of survival of the most heat resistant C. botulinum spores to 10-12. This helps to determine the time required at process temperature of 121oC to reduce spores of C. botulinum).

What is F sub o?

To help your facility get the most out of your autoclave, we introduce the sixth article in our Steam Sterilization Cycles series: The F0 Cycle (pronounced f-sub-zero or f-sub-oh). The term “F0 ” is defined as the number of equivalent minutes of steam sterilization at 250°F (121°C) delivered to a load (product)1.

What is F value in thermal processing?

The F value\**\ for a process is the number of minutes required to kill a known population of microorganisms in a given food under specified conditions. The actual processing time a can of food is given in a retort is always greater than the F value due to heat penetration requirements.

What is 12D reduction?

12D concept refers to thermal processing requirements designed to reduce the probability of survival of the most heat resistant C. botulinum spores to 10-12. This helps to determine the time required at process temperature of 121oC to reduce spores of C.

What is the effect of Z value on F value?

The z value for spore death time typically ranges between 16 to 20 F. As shown in fig. 2, z = 18 F, and indicates that if a process is raised 18 F, the processing time can be lowered one log cycle (10 to 1 min. for this example) and still have an equivalent process.

How is D-value calculated?

The D-value was determined from the inactivation kinetic curve given by the equation: t = D × (log No-log Nf) = D × n [1], where D = D-value (min) at specified conditions, No = bioburden of the chosen bacterium as the BI; Nf = surviving population after an exposure time, t (min), to the selected disinfectant and n = ( …