Why is MCHC low in iron deficiency anemia?

The most common cause of low MCHC is anemia. Hypochromic microcytic anemia commonly results in low MCHC. This condition means your red blood cells are smaller than usual and have a decreased level of hemoglobin.

Is MCHC high or low in iron deficiency anemia?

MCHC results are most helpful when used in conjunction with other red blood cell indices, especially MCV. For instance, low MCHC and low MCV could indicate iron-deficiency anemia, thalassemia, sideroblastic anemia, or lead poisoning. A high MCHC and low MCV could indicate spherocytosis or sickle cell disease.

Is RDW normal in iron deficiency anemia?

Normal value for RDW in adults and children is 11.5\%- 14.5\% and for infants is 15.1-16\%. Out of total 100 cases RDW was abnormal in 98\% cases. In moderate and severe iron deficiency anemia all cases were having RDW in abnormal range while in mild cases of iron deficiency anemia 91.3\% cases had abnormal RDW.

Is RDW increased in thalassemia?

Consequently, RDW tends to be higher in iron deficiency anemia than in thalassemia minor(5), although the role of RDW as an auxiliary parameter in the differentiation of types of anemia is controversial.

What is macrocytic anemia?

Macrocytic anemia, then, is a condition in which your body has overly large red blood cells and not enough normal red blood cells. Different types of macrocytic anemia can be classified depending on what’s causing it. Most often, macrocytic anemias are caused by a lack of vitamin B-12 and folate.

What does a low MCHC mean in a blood test?

A low mean corpuscular hemoglobin concentration (MCHC) shows that someone’s red blood cells do not have enough hemoglobin. Hemoglobin is an iron-rich protein, and a lack of it may indicate anemia. Hemoglobin is responsible for the red color in blood and for circulating oxygen around the body.

How do I know if I have iron deficiency thalassemia?

The two best measures or calculations from the CBC are the Red Blood Cell count alone (RBC) and the Mentzer Index (MCV/RBC). An RBC above 5 x 1012/l is often seen in thalassemia, while a count <5 is more typical of iron deficiency.

What type of anemia is beta thalassemia?

People with beta thalassemia intermedia have moderately severe anemia and some will need regular blood transfusions and other medical treatment. The blood transfusions deliver healthy hemoglobin and RBCs to the body. Beta thalassemia major (also called Cooley’s anemia).

What are 3 types of anemia?

Types

• Aplastic anemia.
• Iron deficiency anemia.
• Sickle cell anemia.
• Thalassemia.
• Vitamin deficiency anemia.