Can typhoid cause liver problems?

Typhoid fever is a very common infectious disease of tropics, associated with high morbidity and mortality. Typhoid fever is often associated with hepatomegaly and mildly deranged liver functions; a clinical picture of acute hepatitis is a rare complication.

What are the long term effects of typhoid?

Untreated typhoid fever may progress to delirium, obtundation, intestinal hemorrhage, bowel perforation, and death within 1 month of onset. Survivors may be left with long-term or permanent neuropsychiatric complications.

How does typhoid affect the intestines?

Intestine perforation is one of the most dreaded and common complication of typhoid fever remarkably so in developing world; it usually leads to diffuse peritonitis, requiring early surgical intervention.

Which organ is most affected in typhoid?

The gastrointestinal tract is more severely affected including liver, spleen, and muscles. Through bloodstream, bacteria can also reach gallbladder, lungs, and kidneys.

Can typhoid cause liver enlargement?

The enlargement of liver in typhoid fever is caused by hypertrophy and hyperplasia of Kupffer’s cells. Tender hepatomegaly observed in 2 of our cases, suggested a more severe hepatocellular in- volvement as both of these cases presented with jaundice.

Can typhoid cause hepatitis?

Typhoid Hepatitis is a rare presentation of typhoid fever, clinically suspected in patients with persistent fever hepatomegaly and jaundice and especially in cases where the liver function tests show predominantly conjugated hyperbilirubinemia, modest elevation of liver enzymes and negative serology for viral hepatitis …

Can typhoid weaken the immune system?

The life-threatening disease typhoid fever results from the ongoing battle between the bacterial pathogen Salmonella and the immune cells of the body. A research group has now uncovered how the typhoid pathogen repeatedly manages to evade the host’s immune system.

Does typhoid affect kidney?

Renal involvement is a rare manifestation of typhoid fever, occurring only in 2–3\% of patients. The spectrum of renal complications in typhoid fever includes cystitis, pyelitis, pyelonephritis, mild proteinuria and, less commonly, mild to severe glomerulonephritis, acute tubular necrosis and interstitial nephritis.

Can typhoid affect digestive system?

The 2 most common complications in untreated typhoid fever are: internal bleeding in the digestive system. splitting (perforation) of a section of the digestive system or bowel, which spreads the infection to nearby tissue.

Is typhoid fever a gastrointestinal disease?

Typhoid fever is not a true intestinal disease, in contrast to non-typhoidal strains of Salmonella. The infection begins with oral ingestion of the bacilli, penetration of the small bowel and then rapidly to the lymphatics and the bloodstream within minutes.

Can typhoid affect kidney?

Does typhoid fever (enteric fever) affect the liver?

The course of liver involvement during the first three weeks of typhoid fever was studied in 20 patients. Previous studies of liver involvement in typhoid fever have not considered the time course of changes.

How does typhoid fever travel through the body?

Once the bacteria that causes typhoid fever is consumed, it travels from the digestive system into the blood.

What are the most serious complications of typhoid fever?

The most serious complications of typhoid fever — intestinal bleeding or holes (perforations) in the intestine — may develop in the third week of illness.

Are there any after effects of tytyphoid?

Typhoid occurs less frequently in the United States and it is more common in developing countries of Africa, Asia and Latin America. There are several after effects of typhoid, even in case of drug treated typhoid. There are some real severe after effects of an untreated typhoid.