How does naltrexone work for alcohol dependence?

Naltrexone was initially used to treat Opioid addiction, including Heroin treatment. Recovering addicts taking Naltrexone no longer experienced the pleasurable sensations association with Opioid use and were therefore less motivated to continue drug abuse. It was discovered that the same was true for alcoholics.

What is the Sinclair Method and how is it supposed to work?

The Sinclair Method requires you to take a naltrexone pill an hour prior to drinking every time you drink. Your brain gradually learns to separate alcohol from the reward of intoxication and so alcohol cravings gradually diminish.

Is the Sinclair Method legit?

Yes, there are stories of “success” with the Sinclair Method. Stories of individuals being “cured” of alcoholism. There is little clinical evidence of this, but rather a fair number of blog postings and YouTube videos.

How long does it take for Sinclair to work?

Every patient responds differently. Most people on TSM will notice a significant decrease within a few weeks. Others take longer (up to 6 months or more). The most important thing is to always take the pill before drinking and to track your results.

What does naltrexone help with?

Naltrexone belongs to a class of drugs known as opiate antagonists. It works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). It also decreases the desire to take opiates. This medication is also used to treat alcohol abuse.

What is naltrexone and how does it work?

Naltrexone is a medication that works in the brain to treat dependence on alcohol or opioids. Naltrexone works by blocking the effect of opioid receptors and decreasing cravings and urges to use alcohol or opioids.

What does Naltrexone help with?

Does naltrexone make you feel good?

Opioids act on brain receptors called opioid receptors. When these receptors are activated, they cause the pleasurable symptom called euphoria. Naltrexone blocks these receptors and stops your brain from feeling the “high” or craving an opioid.