How long does motor neurone disease take to develop?

The symptoms of motor neurone disease begin gradually over weeks and months, usually on one side of the body initially, and get progressively worse.

What are the symptoms of upper motor neuron disease?

Damage to upper motor neurons leads to a group of symptoms called upper motor neuron syndrome:

• Muscle weakness. The weakness can range from mild to severe.
• Overactive reflexes. Your muscles tense when they shouldn’t.
• Tight muscles. The muscles become rigid and hard to move.
• Clonus.
• The Babinski response.

What is the most common motor neuron disease?

Each kind of motor neuron disease affects different types of nerve cells or has a different cause. ALS is the most common of these diseases in adults.

How can you tell the difference between upper and lower motor neuron lesions?

An upper motor neuron lesion is a lesion of the neural pathway above the anterior horn of the spinal cord or motor nuclei of the cranial nerves. A Lower motor neuron lesion is a lesion which affects nerve fibers traveling from the anterior horn of the spinal cord to the associated muscle(s).

What are the four types of motor neuron disorders?

The disease can be classified into four main types depending on the pattern of motor neurone involvement and the part of the body where the symptoms begin.

• Amyotrophic lateral sclerosis (ALS)
• Progressive bulbar palsy (PBP)
• Progressive muscular atrophy (PMA)
• Primary lateral sclerosis (PLS)

Is fatigue a symptom of MND?

Fatigue is common with MND. Factors that may lead to fatigue include immobility, overexertion, sleep disruption, pain, weakened breathing, stress, anxiety, smoking, alcohol and some medications. Symptoms of fatigue include slower speech and movement, shortness of breath and lack of interest in daily planning.

Do you feel ill with MND?

MND is generally not a painful condition, but muscle stiffness can be uncomfortable at times. Some people experienced twinges, aches and cramps. (See also ‘First symptoms of MND’). Getting stiff after sitting still for a long time or trying to get comfortable in bed were common difficulties.

Can a blood test detect motor neurone disease?

There is no blood test to diagnose MND.